Siddhartha Mukherjee

En 2010, siete millones de personas murieron de cáncer en todo el mundo. Con esta fría estadística Siddhartha Mukherjee, médico e investigador oncológico, arranca su amplia y absorbente «biografía»,

Magnífico, necesario y absorbente, Siddhartha Mukherjee, ganador del Premio Pulitzer por El emperador de todos los males, ha escrito una extraordinaria «biografía» del gen y una respuesta a una de la

Tras los éxitos de El emperador de todos los males y El gen, Siddhartha Mukherjee se adentra en la increíble y apasionante historia de la célula. «En un relato a la vez lírico y amplio, Mukherjee nos

A fast‑paced mystery where a detective races against time to solve a disappearance linked to a dark past.

Magnífico, necesario y absorbente, Siddhartha Mukherjee, ganador del Premio Pulitzer por El emperador de todos los males, ha escrito una extraordinaria «biografía» del gen y una respuesta a una de la

Un libro esencial para médicos y enfermeras, y de gran utilidad para sus pacientes. Un libro de la serie TED Books que busca reflexionar sobre la naturaleza de la medicina como ciencia y sobre los principios que deben regir las relaciones entre profesionales y pacientes.El autor destaca tres principios que gobiernan la practica de la medicina y que deben ser conocidos por todos para mejorar la atencion de los pacientes y para conseguir que todos vivamos mas sanos.

Magnífico, necesario y absorbente, Siddhartha Mukherjee, ganador del Premio Pulitzer porEl emperador de todos los males, ha escrito una extraordinaria «biografía» del gen y una respuesta a una de la

Longlisted for the Baillie Gifford Prize 2023**A NEW YORK TIMES, DAILY TELEGRAPH, ECONOMIST, MAIL ON SUNDAY and GUARDIAN BOOK OF THE YEARFrom the dawn of life itself, every being that has ever lived owes its existence to the cell.''Will leave you in awe'' GuardianThe discovery of this vital form led to a transformation in medicine but also in our understanding of ourselves - not as bodies or machines but as ecosystems. It has also given us the power to treat a vast array of mortal maladies...and even to create new kinds of human altogether.Rich with stories of scientists, doctors and the patients whose lives may be saved by their work, The Song of the Cell is a stunning ode to the building blocks of life and the cutting-edge science harnessing their power for the better.

En 2010, siete millones de personas murieron de cáncer en todo el mundo. Con esta fría estadística Siddhartha Mukherjee, médico e investigador oncológico, arranca su amplia y absorbente «biografía»

Un libro esencial para médicos y enfermeras, y de gran utilidad para sus pacientes. Un libro de la serie TED Books que busca reflexionar sobre la naturaleza de la medicina como ciencia y sobre los principios que deben regir las relaciones entre profesionales y pacientes.El autor destaca tres principios que gobiernan la practica de la medicina y que deben ser conocidos por todos para mejorar la atencion de los pacientes y para conseguir que todos vivamos mas sanos.

Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the worlds premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicineand how understanding these principles can empower us all.Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a science? Sciences must have lawsstatements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences?Dr. Mukherjee has spent his career pondering this questiona question that would ultimately produce some of most serious thinking he would do around the tenets of his disciplineculminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine.Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjees signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.

Winner of the 2023 PROSE Award for Excellence in Biological and Life Sciences and the 2023 Chautauqua Prize! Named a New York Times Notable Book and a Best Book of the Year by The Economist, Oprah Daily, BookPage, Book Riot, the New York Public Library, and more!In The Song of the Cell, the extraordinary author of the Pulitzer Prizewinning The Emperor of All Maladies and the #1 New York Times bestseller The Gene blends cutting-edge research, impeccable scholarship, intrepid reporting, and gorgeous prose into an encyclopedic study that reads like a literary page-turner (Oprah Daily).Mukherjee begins this magnificent story in the late 1600s, when a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek looked down their handmade microscopes. What they saw introduced a radical concept that swept through biology and medicine, touching virtually every aspect of the two sciences, and altering both forever. It was the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selveshearts, blood, brainsare built from these compartments. Hooke christened them cells.The discovery of cellsand the reframing of the human body as a cellular ecosystemannounced the birth of a new kind of medicine based on the therapeutic manipulations of cells. A hip fracture, a cardiac arrest, Alzheimers dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID pneumoniaall could be reconceived as the results of cells, or systems of cells, functioning abnormally. And all could be perceived as loci of cellular therapies.Filled with writing so vivid, lucid, and suspenseful that complex science becomes thrilling, The Song of the Cell tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. Told in six parts, and laced with Mukherjees own experience as a researcher, a doctor, and a prolific reader, The Song of the Cell is both panoramic and intimatea masterpiece on what it means to be human.In an account both lyrical and capacious, Mukherjee takes us through an evolution of human understanding: from the seventeenth-century discovery that humans are made up of cells to our cutting-edge technologies for manipulating and deploying cells for therapeutic purposes (The New Yorker).

The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate HistoryNow includes an excerpt from Siddhartha Mukherjees new book Song of the Cell!From the Pulitzer Prizewinning author of The Emperor of All Maladiesa fascinating history of the gene and a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick (Elle).Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself. Ken BurnsDr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.Mukherjee expresses abstract intellectual ideas through emotional stories[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry (The Washington Post). Throughout, the story of Mukherjees own familywith its tragic and bewildering history of mental illnessreminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentationfrom Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome.A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we areand what our manipulation of those genes might mean for our future (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. The Gene is a book we all should read (USA TODAY).

The Emperor of All Maladies is a magnificent, profoundly humane biography of cancerfrom its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologists precision, a historians perspective, and a biographers passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived withand perished fromfor more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out war against cancer. The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave may have cut off her diseased breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjees own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to surviveand to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is an extraordinary achievement (The New Yorker)a magnificent, profoundly humane biography of cancerfrom its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence.Now includes an excerpt from Siddhartha Mukherjees new book Song of the Cell!Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologists precision, a historians perspective, and a biographers passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived withand perished fromfor more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out war against cancer. The book reads like a literary thriller with cancer as the protagonist.Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

¿Qué pasará cuando dominemos completamente nuestro genoma?¿Podremos crear, en nombre de la ciencia, posthumanos capaces de superar las enfermedades que nos asolan en la actualidad?Siddhartha Mukherjee, ganador del Premio Pulitzer por El emperador de todos los males, nos ofrece una detallada vision de lo que puede a llegar a convertirse la raza humana si es que, en el futuro, todavia podemos llamarla asi.Sobre El gen: Esta quiza sea la mejor historia de suspense jamas contada, una busqueda de milenios dirigida por mil exploradores, de Aristoteles a Mendel a Francis Collins, tras el enigma en el centro de cada celula. Como El emperador de todos los males, El gen es prodigiosa, torrencial y finalmente transcendente. Si te interesa en que consiste ser humano hoy y en todos los mañanas que vengan, tienes que leer este libro. Anthony Doerr, autor de La luz que no puedes verEl gen es una magnifica sintesis de la ciencia de la vida, y nos obliga a enfrentarnos con el nucleo de esa ciencia, asi como con los retos eticos y filosoficos a nuestra idea de en que consiste ser humano. Paul Berg, Premio Nobel de QuimicaMagnifico... La historia del gen se ha contado por trozos de distintas maneras, pero nunca con la perspectiva y la grandeza que Mukherjee aporta a su historia. James Gleick, New York Times Book Review

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjees revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writers exploration of what it means to be human.Mukherjee begins this magnificent story in the late 1600s, when a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek looked down their handmade microscopes. What they saw introduced a radical concept that swept through biology and medicine, touching virtually every aspect of the two sciences, and altering both forever. It was the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selveshearts, blood, brainsare built from these compartments. Hooke christened them cells.The discovery of cellsand the reframing of the human body as a cellular ecosystemannounced the birth of a new kind of medicine based on the therapeutic manipulations of cells. A hip fracture, a cardiac arrest, Alzheimers dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID pneumoniaall could be reconceived as the results of cells, or systems of cells, functioning abnormally. And all could be perceived as loci of cellular therapies.In The Song of the Cell, Mukherjee tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. He seduces you with writing so vivid, lucid, and suspenseful that complex science becomes thrilling. Told in six parts, laced with Mukherjees own experience as a researcher, a doctor, and a prolific reader, The Song of the Cell is both panoramic and intimatea masterpiece.

An epic, dazzling history of the idea that defines us.From Gregor Mendels pea plants to the discovery of DNA and the CRISPR revolution in gene-editing, The Gene tells the story of how we came to understand heredity to decipher the master-code that makes and defines humans land how that knowledge now allows us to rewrite life itself. Siddhartha Mukherjee combines scientific insight with personal history, weaving in his own familys struggles with mental illness to explore the moral frontiers of genetics.This is science writing of the highest order, humane, lyrical, and profound, showing how the study of genes illuminates both our biological destiny and our deepest hopes.Siddhartha Mukherjee is the perfect guide to genome science Bill GatesThrilling and comprehensive Sunday Times

WINNER OF THE GUARDIAN FIRST BOOK AWARD 2011WINNER OF THE PULITZER PRIZE FOR NON-FICTION 2011 Profound, eloquent and searching SUNDAY TIMES Essential reading INDEPENDENT Masterly GUARDIAN Extraordinary NEW YORK TIMES BOOK REVIEW AN OBSERVER BEST BOOK OF THE CENTURY SO FARRiveting, audacious and now more urgent than ever in this vast update, The Emperor of All Maladies is a masterpiece. The story of cancer is a human one a tale of chance discoveries, seized opportunities and human endurance. From innovative early surgeries to the Curies ultimately tragic work with radiation; from Sidney Farbers hugely risky discovery of chemotherapy to the authors treatment of his own patients, The Emperor of All Maladies is a profound and revelatory portrait of an enigmatic disease humans have lived with, and perished from, for more than five thousand years. In this updated edition of Siddhartha Mukherjees instant classic, four new chapters reveal what has changed in the universe of cancer in the years since the book was first published. With moving eloquence, he offers an insight into our evolving understanding of cancers causes and the emerging, revolutionary new treatments that might shape its future, including those that Mukherjee himself has helped devise. This elegantly written overview allows us to look a once whispered-about illness squarely in the eye INDEPENDENT The notion of "popular science" doesnt come close to describing this achievement. It is literature OBSERVER

En 2010, siete millones de personas murieron de cáncer en todo el mundo. Con esta fría estadística Siddhartha Mukherjee, médico e investigador oncológico, arranca su amplia y absorbente «biografía»,